Hedgehog Signaling Pathway Database
 
sonic hedgehog, Homo sapiens
Orthologs:Drosophila melanogaster, Mus musculus, Danio rerio, Gallus gallus, Rattus norvegicus, Pan troglodytes, Achaearanea tepidariorum, Ambystoma mexicanum, Amblypharyngodon hornae, Anopheles gambiae, Artemia franciscana, Astyanax fasciatus, Bos taurus, Branchiostoma belcheri, Branchiostoma floridae, Carassius auratus, Ciona intestinalis, Coturnix coturnix, Cynops pyrrhogaster, Cyprinus carpio, Danio aequipinnatus, Danio aff, Danio devario, Danio frankei, Danio kerri, Danio malabaricus, Danio pathirana, Danio pulcher, Danio cf, Drosophila hydei, Drosophilia melangaster, Drosophila pseudoobscura, Eleutherodactylus coqui, Equus caballus, Euscorpius flavicaudis, Glomeris marginata, Gryllus bimaculatus, Helobdella robusta, Hemicentrotus pulcherrimus, Hirudo medicinalis, Hydra vulgaris, Ilyanassa obsoleta, Junonia coenia, Lampetra japonica, Lytechinus variegatus, Macaca fascicularis, Meriones unguiculatus, Notophthalmus viridescens, Onchorhynchus mykiss, Oryzias latipes, Paralichthys olivaceus, Patella vulgata, Pleurodeles waltl, Pseudorasbora parva, Puntius conchonius, Puntius tetrazona, Rana catesbeiana, Rasbora elegans, Rasbora heteromorpha, Rasbora paviei, Saimiri boliviensis, Scyliorhinus canicula, Suncus murinus, Strongylocentrotus purpuratus, Takifugu rubripes, Tanichthys albonubes, Trachemys scripta, Tribolium castaneum, Trionyx sinensis, Xenopus lavis,
Related subclasses:dhh, ihh
Synonyms:shh, HHG1, HLP3, HPE3, SMMCI
Evidence of Pathway Affiliation

HMM Domains

Pfam Hh-NSMART Hh-NSMART Hint-N
 6.80E-1254.50E-32
SequencesmRNA:GenBank
protein: NCBI, SwissProt
Genomic OrganizationChromosome 7: UCSC genome, NCBI

Transcript structure:

source: Ensembl
Protein Motifs Hedgehog, Hint, Endopeptidase
Size
Bubblogramsignal peptide: 1 to 22 Pfam:HH_signal: 24 to 184 Unknown region: 185 to 195 HintN: 196 to 319 HintC: 324 to 369 low complexity region: 373 to 393 low complexity region: 396 to 412 low complexity region: 414 to 431 Unknown: 432 to 462

Source: SMART


BLAST
Proteome Browser: UCSC
Protein Family: pfam-Hh, Hint
Protein Sub-domains: InterPro
Phenotypes & DiseasesOMIM
ReagentsAntibody Index
Microarray DataProfile: UCSC
NCBI: GEO
mRNA ExpressionNCI: CGAP
ReferencesPubMed
Database LinksGenome report: UCSC
Stanford SOURCE
AceView
Ensembl GeneView
     

Last updated 28-Aug-2006

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