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| Gli | Animal | Transgenic mouse model of basal cell carcinoma | 6689937 | active | | | Hui; Chi-Chung ; Dlugosz; Andrzej A. | abstract |
| Dlx | Cell | Production of gabaergic cells | 6602680 | active | | | Rubenstein; John L. ; Mione; Marina ; Anderson; Stewart ; Stuehmer; Thorsten ; Yun; Kyuson | abstract |
| | Composition | Composition of a polypeptide and an amphiphilic compound in an ionic complex and the use thereof | 6867182 | active | 03/15/2005 | 09/17/2001 | Papadimitriou; Apollon | abstract |
| shh, ihh, dhh | Compositions | Compositions comprising hedgehog proteins | 6630148 | active | | | Ingham; Philip W. ; McMahon; Andrew P. ; Tabin; Clifford J. | abstract |
| shh, ihh, dhh | embryonic | Vertebrate embryonic pattern-inducing proteins and uses related thereto | 5789543 | active | 08/04/1998 | December 30, 1993 | Ingham; Philip W. ; McMahon; Andrew P. ; Tabin; Clifford J. (Cambridge, MA | abstract |
| shh, ihh, dhh | embryonic | Vertebrate embryonic pattern-inducing proteins | 6384192 | active | | | Ingham; Philip W. ; McMahon; Andrew P. ; Tabin; Clifford J. | abstract |
| shh, ihh, dhh, Mhh | embryonic | Vertebrate embryonic pattern-inducing proteins and uses related thereto | 6607913 | active | | | Ingham; Philip W. ; McMahon; Andrew P. ; Tabin; Clifford J. | abstract |
| shh | Gene | Mutant human hedgehog gene | 5759811 | active | 06/02/1998 | 11/13/1996 | Epstein; Ervin ; Hu; Zhilan ; Bonifas; Jeanette | abstract |
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| ptc | Gene | Patched genes and their use | 5837538 | active | 11/17/1998 | 10/06/1995 | Scott; Matthew P ; Goodrich; Lisa V. ; Johnson; Ronald L. | abstract |
| Fu | Gene | Fused | 6022708 | active | | | de Sauvage; Frederic ; Rosenthal; Arnon | abstract |
| ptc | Gene | Patched genes and their use for diagnostics | 6027882 | active | | | Scott; Matthew P. ; Goodrich; Lisa V. ; Johnson; Ronald L. ; Epstein; Ervin ; Oro; Tony | abstract |
| Cos2 | Gene | Costal2 genes and their uses | 6218144 | active | | | Scott; Matthew P. ; Sisson; John C. | abstract |
| pt2 | Gene | Patched-2 | 6348575 | active | | | de Sauvage; Frederic ; Carpenter; David A. | abstract |
| ptc | Gene | Patched genes and uses related thereto | 6429354 | active | | | Scott; Matthew P. ; Goodrich; Lisa V. ; Johnson; Ronald L. ; Epstein, Jr.; Ervin | abstract |
| SuFu | Gene | Molecules associated with the human suppressor of fused gene | 6448020 | active | | | Toftgard; Rune ; Zaphiropoulos; Peter G. ; Kogerman; Priit ; Grimm; Thomas | abstract |
| ptc | Gene | Patched genes and uses related thereto | 6551782 | active | | | Scott; Matthew P. ; Goodrich; Lisa V. ; Johnson; Ronald L. ; Epstein, Jr.; Ervin | abstract |
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| Ptc | Gene | Basal cell carcinoma tumor supressor gene | 6552181 | active | | | Dean; Michael Carlton ; Hahn; Heidi Eve ; Wicking; Carol ; Christiansen; Jeffrey ; Zaphiropoulos; Peter G ; Gailani; Mae R. ; Shanley; Susan Mary ; Chidambaram; Abirami ; Vorechovsky; Igor ; Holmberg-Lindstrom; Erika ; Unden; Anne Birgitte ; Gillies; Susan Alana ; Negus; Kylie ; Smyth; Ian Mcleod ; Pressman; Carol Leah ; Leffell; David J. ; Gerrard; Bernard ; Goldstein; Alisa Miriam ; Wainwright; Brandon ; Toftgard; Rune Carl-Magnus ; Chenevix-Trench; Georgia ; Bale; Allen E. | abstract |
| nkd | Gene | Naked cuticle genes and their uses | 6630323 | active | | | Scott; Matthew ; Zeng; Wenlin ; Wharton; Keith | abstract |
| Ptc2 | Gene | Component in the hedgehog signalling pathway | 6881833 | active | 04/19/2005 | 07/09/2001 | Zaphiropoulos; Peter G. ; Unden; Anne Birgitte ; Toftg.ang.rd; Rune ; Rahnama; Fahimeh ; Hollingsworth; Robert E. | abstract |
| ptc2 | Gene/Nucleic acids | Patched-2 polypeptides and polynucleotides | 6051400 | active | | | Kelsell; David P ; Barnes; Michael R ; Testa; Tania Tamson | abstract |
| ptch | Gene/protein | Human patched genes and proteins, and uses related thereto | 6605700 | active | | | Bumcrot; David A. | abstract |
| shh, ihh, dhh | Hh signaling | Cholesterol and hedgehog signaling | 6288048 | active | | | Beachy; Philip A. ; Porter; Jeffrey A. ; Cooper; Michael K. | abstract |
| hh,shh,ihh,ehh,dhh,twhh | Hh signaling | Hydrophobically-modified hedgehog protein compositions and methods | 6444793 | active | 09/03/2002 | 06/03/1999 | Pepinsky; R. Blake ; Baker; Darren P. ; Wen; Dingyi ; Williams; Kevin P. ; Garber; Ellen A. ; Taylor; Frederick R. ; Galdes; Alphonse ; Porter; Jeffrey | abstract |
| shh, ihh, dhh | Hh signaling | Active hedgehog protein conjugate | 6818623 | active | 11/16/2004 | 10/21/2002 | Esswein; Angelika ; Lang; Kurt ; Rueger; Petra ; Seytter; Tilman | abstract |
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| hh,shh,ihh,ehh,dhh,twhh | Hh signaling | Hydrophobically-modified protein compositions and methods | 6897297 | active | 05/24/2005 | 05/26/2000 | Pepinsky; R. Blake ; Zeng; Chenhui ; Baker; Darren P. ; Wen; Dingyi ; Williams; Kevin P. ; Garber; Ellen A. ; Strauch; Kathryn L. ; Taylor; Frederick R. ; Weinreb; Paul H. ; Petter; Russell C. ; Galdes; Alphonse ; Porter; Jeffrey | abstract |
| shh, ihh, dhh | Hh signaling | Hedgehog-derived polypeptides | 6911528 | active | 06/28/2005 | 05/02/2000 | Beachy; Philip A. ; Porter; Jeffrey A. | abstract |
| shh, ihh, dhh | Method | Method of identifying compounds affecting hedgehog cholesterol transfer | 6057091 | active | | | Beachy; Philip A. ; Porter; Jeffrey A. | abstract |
| ptc, smo | Method | Method of modulating hair growth | 6159950 | active | | | Crystal; Ronald G. ; Sato; Noboru ; Leopold; Philip L. | abstract |
| shh, ihh, dhh | Method | Pharmaceutical compositions containing hedgehog protein | 6207718 | active | | | Papadimitriou; Apollon | abstract |
| shh, ihh, dhh | Method | Method of using hedgehog polypeptides to regulate neuronal cell growth | 6214794 | active | | | Beachy; Philip A. ; Moon; Randall T. ; Porter; Jeffrey A. | abstract |
| Gli1 | Method | Methods and materials for the diagnosis and treatment of sporadic basal cell carcinoma | 6238876 | active | | | Altaba; Ariel Ruiz i | abstract |
| hre | Method | Method for identifying a hedgehog-mediated phosphorylation state dependent transcription factor | 6277566 | active | | | Beachy; Phillip A. ; Tsai; Ming-Jer ; Tsai; Sophia Y. ; Krishnan; Venkatesh ; Chen; Chen-Huan | abstract |
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| shh | Method | Method of dopaminergic and serotonergic neuron formation from neuroprogenitor cells | 6277820 | active | | | Rosenthal; Arnon ; Hynes; Mary A. ; Ye; Weilan | abstract |
| shh, ihh, dhh | Method | Method of promoting chondrocyte differentiation with hedgehog related polypeptides | 6610656 | active | | | Ingham; Philip W. ; McMahon; Andrew P. ; Tabin; Clifford J. | abstract |
| ptc, smo, | Method | Methods of modulating lipid metabolism and storage | 6616926 | active | | | Burkly; Linda ; Wang; Li Chun | abstract |
| shh, ihh, dhh | Method | Cardiovascular components for transplantation and methods of making thereof | 6695879 | active | | | Bell; Eugene | abstract |
| shh, ihh, dhh | Method | Methods of using hedgehog proteins to modulate hematopoiesis and vascular growth | 6713065 | active | | | Baron; Margaret H. ; Farrington; Sarah M. ; Belaoussoff; Maria | abstract |
| hre | Method | Method for identifying an agent that affects a hedgehog signaling pathway | 6733971 | active | | | Beachy; Philip A. ; Tsai; Ming-Jer ; Tsai; Sophia ; Krishnan; Venkatesh ; Chen; Chien-Huan | abstract |
| shh, ihh, dhh, ptc | Method | Neuroprotective methods and reagents | 6767888 | active | | | Mahanthappa; Nagesh K. | abstract |
| | Method | Lineage-restricted neuronal precursors and methods of isolation | 6787353 | active | | | Rao; Mahendra S. ; Mayer-Proschel; Margot ; Kalyani; Anjali J. | abstract |
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| shh | Method | Making neural cells for human therapy or drug screening from human embryonic stem cells | 6833269 | active | | | Carpenter; Melissa K. | abstract |
| shh,ihh,dhh | Method | Structure-based screening techniques for drug discovery | 6864359 | active | 03/08/2005 | February 11, 2000 | Luo; Peizhi | abstract |
| shh | Method | Muscle-derived cells (MDCs) for treating muscle-or bone-related injury or dysfunction | 6866842 | active | 03/15/2005 | 04/30/1999 | Chancellor; Michael B. ; Huard; Johnny | abstract |
| shh,twhh | Method | Inhibition of gene expression using polynucleotide analogues | 6867349 | active | 03/15/2005 | July 30, 2001 | Ekker; Stephen C.; Nasevicius; Aidas ; Kim; Hyon ; Sumanas; Saulius | abstract |
| ihh | Method | Genes differentially expressed in secretory versus proliferative endometrium | 6884578 | active | 04/26/2005 | 12/11/2000 | Warrington; Janet A.; Mahadevappa; Mamatha | abstract |
| hh,shh,ihh,ehh,dhh,twhh | Method | Methods and compositions for treating or preventing peripheral neuropathies | 6884770 | active | 04/26/2005 | 05/11/2000 | Galdes; Alphonse ; Mahanthappa; Nagesh | abstract |
| hh,shh,ihh,ehh,dhh,twhh, ptc | Method | Methods and compositions for regulating skeletogenic formation | 6884775 | active | 04/26/2005 | 08/01/1997 | Tabin; Clifford J. ; McMahon; Andrew P. ; Ingham; Philip W. ; Vortkamp; Andrea M. | abstract |
| shh, ihh, dhh | Method | Use of a melanoma inhibiting activity factor (MIA) for cartilage and bone repair | 6890897 | active | | | Dony; Carola ; Proetzel; Gabriele ; Leser-Reiff; Ulrike | abstract |
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| shh, ihh, dhh | Method | Methods to stimulate insulin production by pancreatic beta-cells | 6903073 | active | 06/07/2005 | 12/08/2000 | Habener; Joel F. ; Thomas; Melissa K. | abstract |
| ptch,shh | Method | Albumin fusion proteins | 6905688 | active | 06/14/2005 | 04/12/2001 | Rosen; Craig A. ; Haseltine; William A. | abstract |
| ror2 | Method | Methods of stimulating cartilage formation | 6908744 | active | | | DeChiara; Thomas M. ; Kimble; Carrie A. ; Yancopoulos; George D. | abstract |
| hh,shh,ihh,ehh,dhh,twhh | method | GENETIC SYSTEM AND SELF-CLEAVING INTEINS DERIVED THEREFROM, BIOSEPARATIONS AND PROTEIN PURIFICATION EMPLOYING SAME, AND METHODS FOR DETERMINING CRITICAL, GENERALIZABLE AMINO ACID RESIDUES FOR VARYING INTEIN ACTIVITY | 6933362 | active | 08/23/2005 | 08/17/2000 | Belfort; Marlene; Belfort; Georges ; Derbyshire; Vicky ; Wood; David ; Wu; Wei | abstract |
| shh,ptc | Method | Method of use of sonic hedgehog protein as a ligand for patched | 6942988 | active | sept.13-05 | 24 Sept,2001 | Beachy; Philip A. | abstract |
| hh,shh,ihh,ehh,dhh,twhh | Nucleic acids | Nucleic acids encoding hedgehog proteins | 6165747 | active | | | Ingham; Philip W. ; McMahon; Andrew P. ; Tabin; Clifford J. ; Bumcrot; David A. ; Marti-Gorostiza; Elisa | abstract |
| hh,shh,ihh,ehh,dhh,twhh | Nucleic acids | Nucleic acids encoding hedgehog proteins | 6271363 | active | | | Ingham; Philip W. ; McMahon; Andrew P. ; Tabin; Clifford J. | abstract |
| hh,shh,ihh,ehh,dhh,twhh | Nucleic acids | Nucleic acids encoding hedgehog proteins | 6664075 | active | | | Ingham; Philip W. ; McMahon; Andrew P. ; Tabin; Clifford J. ; Bumcrot; David A. ; Marti-Gorostiza; Elisa | abstract |
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| ptc2 | Nucleic acids | Nucleic acid encoding patched-2 | 6709838 | active | | | de Sauvage; Frederic ; Carpenter; David A. | abstract |
| shh, ihh, dhh | polypeptides | Hedgehog-derived polypeptides | 6132728 | active | | | Beachy; Philip A. ; Moon; Randall T. ; Porter; Jeffrey A. | abstract |
| shh, ihh, dhh | polypeptides | Hedgehog-derived polypeptides | 6281332 | active | | | Beachy; Philip A. ; Moon; Randall T. | abstract |
| ptc2 | polypeptides | Patched-2 polypeptide | 6353092 | active | | | Kelsell; David P ; Barnes; Michael R ; Testa; Tania Tamson (London, GB | abstract |
| fu | polypeptides | Fused polypeptides | 6451977 | active | | | de Sauvage; Frederic ; Rosenthal; Arnon | abstract |
| fu | polypeptides | Fused polypeptides | 6531579 | active | | | de Sauvage; Frederic ; Rosenthal; Arnon | abstract |
| ptc | polypeptides | Polynucleotides encoding patched proteins | 6610507 | active | | | Scott; Matthew P. ; Goodrich; Lisa V. ; Johnson; Ronald L. | abstract |
| smo | proteins | Vertebrate smoothened proteins | 5990281 | active | | | de Sauvage; Frederic J. ; Rosenthal; Arnon ; Stone; Donna M. | abstract |
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| vhh-1 | proteins | Rat hedgehog protein-1 (Vhh-1) | 6235885 | active | | | Jessell; Thomas M. ; Dodd; Jane ; Roelink; Henk ; Edlund; Thomas | abstract |
| smo | proteins | Vertebrate smoothened proteins | 6492139 | active | | | de Sauvage; Frederic J. ; Rosenthal; Arnon ; Stone; Donna M. (Brisbane, CA | abstract |
| hip | proteins | Hedgehog interacting proteins and uses related thereto | 6514724 | active | | | McMahon; Andrew P. ; Chuang; Pao-Tien | abstract |
| shh, ihh, dhh | proteins | Vertebrate tissue pattern-inducing proteins, and uses related thereto | 6576237 | active | | | Ingham; Philip W. ; McMahon; Andrew P. ; Tabin; Clifford J. ; Bumcrot; David A. ; Marti-Gorostiza; Elisa | abstract |
| ptc, shh, ihh, dhh | Regulation of Tissue | Regulation of epithelial tissue by hedgehog-like polypeptides, and formulations and uses related thereto | 6639051 | active | | | Wang; Elizabeth A. | abstract |
| smo | Regulators of the hedgehog pathway | Antibodies to vertebrate smoothened proteins | 6136958 | active | | | de Sauvage; Frederic J. ; Rosenthal; Arnon ; Stone; Donna M. | abstract |
| ptc | Regulators of the hedgehog pathway | Patched antibodies | 6172200 | active | | | Scott; Matthew P. ; Goodrich; Lisa V. ; Johnson; Ronald L. | abstract |
| smo, ptc | Regulators of the hedgehog pathway | Regulators of the hedgehog pathway, compositions and uses related thereto | 6291516 | active | | | Dudek; Henryk ; Ji; Benxiu | abstract |
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| smo | Regulators of the hedgehog pathway | Vertebrate smoothened antibodies | 6407216 | active | | | de Sauvage; Frederick J. ; Rosenthal; Arnon ; Stone; Donna M. | abstract |
| ptc, smo | Regulators of the hedgehog pathway | Inhibitors of hedgehog signaling pathways, compositions and uses related thereto | 6432970 | active | | | Beachy; Philip A. ; Cooper; Michael K. ; Porter; Jeffrey A. | abstract |
| hh,shh,ihh,ehh,dhh,twhh | Regulators of the hedgehog pathway | Active hedgehog protein conjugate | 6468978 | active | 10/22/2002 | April 28, 1999 | Esswein; Angelika ; Lang; Kurt ; Rueger; Petra ; Seytter; Tilman (Graefelfing, | abstract |
| ptc | Regulators of the hedgehog pathway | Mediators of hedgehog signaling pathways, compositions and uses related thereto | 6545005 | active | | | Baxter; Anthony David ; Boyd; Edward Andrew ; Guicherit; Oivin M. ; Price; Stephen ; Rubin; Lee D. | abstract |
| ptc | Regulators of the hedgehog pathway | Mediators of hedgehog signaling pathways, compositions and uses related thereto | 6552016 | active | | | Baxter; Anthony David ; Boyd; Edward Andrew ; Guicherit; Oivin M. ; Price; Stephen ; Rubin; Lee | abstract |
| smo, ptc | Regulators of the hedgehog pathway | Small organic molecule regulators of cell proliferation | 6613798 | active | | | Porter; Jeffrey ; Guicherit; Oivin M. ; Rubin; Lee ; Baxter; Anthony David ; Boyd; Edward Andrew ; Price; Stephen | abstract |
| ptc, smo | Regulators of the hedgehog pathway | Agonists of hedgehog signaling pathways and uses related thereto | 6683108 | active | 01/27/2004 | 11/28/2000 | Baxter; Anthony David ; Boyd; Edward Andrew ; Guicherit; Oivin M. ; Porter; Jeffrey ; Price; Stephen ; Rubin; Lee | abstract |
| smo, ptc | Regulators of the hedgehog pathway | Small organic molecule regulators of cell proliferation | 6683192 | active | | | Baxter; Anthony David ; Boyd; Edward Andrew ; Guicherit; Oivin M. ; Porter; Jeffrey ; Price; Stephen ; Rubin; Lee ; Stibbard; John Harry Alexander | abstract |
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| smo, ptc | Regulators of the hedgehog pathway | Regulators of the hedgehog pathway, compositions and uses related thereto | 6686388 | active | | | Dudek; Henryk ; Ji; Benxiu | abstract |
| ptc, smo | Regulators of the hedgehog pathway | Inhibitors of hedgehog signal pathways, compositions and uses related thereto | 6867216 | active | 03/15/2005 | 11/08/2000 | Beachy; Philip A. ; Cooper; Michael K. ; Porter; Jeffrey A. | abstract |
| | Screening | Screening assays for hedgehog agonists and antagonists | 6261786 | active | | | Marigo; Valeria ; Tabin; Clifford J. ; Ingham; Philip W. ; McMahon; Andrew P. | abstract |
| | Screening | Function-based small molecular weight compound screening system in drosophila melanogaster | 6548733 | active | | | Hafen; Ernst | abstract |
| hh,shh,ihh,ehh,dhh,twhh | sequence | Vertebrate embryonic pattern-inducing proteins, and uses related thereto | 5844079 | active | 12/01/1998 | December 14, 1994 | Ingham; Philip W. ; McMahon; Andrew P. ; Tabin; Clifford J. | abstract |
| ptc,ptch | sequence | Patched genes and uses related thereto | 6921646 | active | 07/26/2005 | 01/03/2001 | Scott; Matthew P. ; Goodrich; Lisa V. ; Johnson; Ronald L. | abstract |
| cos2 (PRO539) | sequence | Secreted and transmembrane polypeptides and nucleic acids encoding the same | 6930172 | active | 08/16/2005 | 12/27/2001 | Ferrara; Napoleone ; Gao; Wei-Qiang ; Goddard; Audrey ; Gurney; Austin L. ; Watanabe; Colin K. ; Wood; William I. | abstract |
| shh | Techniques | Identification and cloning of a new subfamily of sulfatases and functional embryonic techniques for characterization of such proteins | 6797816 | active | | | Emerson; Charles P. ; Dhoot; Gurtej Kaur (London | abstract |
